ARP984-11 [Polyclonal Antibody]
CDC2L1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB ELISA
Immunogen Range:   A synthetic peptide corresponding to N-terminus of human CDK11B
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   984
Swiss Prot:   P06493
Synonyms:   CDC2L2, CDK11, CDK11-p110, CDK11-p46, CDK11-p58, CLK-1, FLJ59152, PK58, p58, p58CDC2L1, p58CLK-1
Purification:   Affinity purification
Storage:   Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information