Species: | Rabbit |
Applications: | WB IHC ELISA IF |
Immunogen Range: | A synthetic peptide corresponding to residues surrounding serine 363 of human TNNI3 |
Clonality: | Polyclonal Antibody |
Isotype: | / |
GENE ID: | 7137 |
Swiss Prot: | P19429 |
Synonyms: | CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI |
Purification: | Affinity purification |
Storage: | Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles. |
Background: | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq |
Caculated MW: | 28 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:500-1:1000 |
Reacitivity: | Human, Mouse, Rat |