ARP2909-11
[Polyclonal Antibody]
GRLF1 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IHC ELISA |
| Immunogen Range: | A synthetic peptide corresponding to internal of human GRLF1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 2909 |
| Swiss Prot: | Q9NRY4 |
| Synonyms: | GRF-1, KIAA1722, MGC10745, P190-A, P190A, p190RhoGAP |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles. |
| Background: | The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq |
| Caculated MW: | 190 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:50-1:100 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information