ARP5350-11
[Polyclonal Antibody]
PLN Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide corresponding to amino acids at N-terminus of human PLN |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 5350 |
| Swiss Prot: | P26678 |
| Synonyms: | CMD1P, PLB |
| Purification: | Affinity purification |
| Storage: | Store at -20°C on dry atmosphere.After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower. |
| Background: | The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq |
| Caculated MW: | 6,12,24 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1 ug/mL |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information