ARP54541-12 [Polyclonal Antibody]
DDIT4 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to internal region 12 amino acids of human DDIT4
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   54541
Swiss Prot:   Q9NX09
Synonyms:   Dig2, FLJ20500, REDD-1, REDD1, RP11-442H21.1, RTP801
Purification:   Affinity purification
Storage:   Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activation of caspases.
Caculated MW:   48 kDa
Observed MW:   Refer to Figures
Applications:   WB 2-4 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information