Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic phosphopeptide corresponding to residues surrounding T34 of BIRC5 |
Clonality: | Polyclonal Antibody |
Isotype: | / |
GENE ID: | 332 |
Swiss Prot: | O15392 |
Synonyms: | API4, EPR-1 |
Purification: | Affinity purification |
Storage: | Store at 4°C in Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.1% sodium azide). Do not freeze |
Background: | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq |
Caculated MW: | 16 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:1000 IF 1:50-1:200 ICC 1:50-1:200 |
Reacitivity: | Bovine, Cat, Dog, Human, Mouse, Pig, Primates |