ARPF010P-11
[Polyclonal Antibody]
Phospho-ERBB2-Tyr1248/EGFR-Tyr1173 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding EGFR (Y1173)/ERBB2 (Y1248) of human |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
1956/2064 |
| Swiss Prot: |
P00533/P04626 |
| Synonyms: |
ERBB, ERBB1, HER1, PIG61, mENA |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq |
| Caculated MW: |
185 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:1800
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!