ARP5159P-12
[Polyclonal Antibody]
Phospho-PDGFRB-Tyr1021 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1021 of human PDGFRB |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
5159 |
Swiss Prot: |
P09619 |
Synonyms: |
CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles. |
Background: |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq |
Caculated MW: |
190 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1800
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!