ARP5159P-15 [Polyclonal Antibody]
Phospho-PDGFRB-Tyr771 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y771 of human PDGFRB
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5159
Swiss Prot:   P09619
Synonyms:   CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1
Purification:   Affinity purification
Storage:   Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
Caculated MW:   190 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1800
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information