ARP203068-11
[Polyclonal Antibody]
TUBB Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IHC |
| Immunogen Range: | A synthetic peptide corresponding to amino acids 416-430 of human TUBB |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 203068 |
| Swiss Prot: | P07437 |
| Synonyms: | M40, MGC117247, MGC16435, OK/SW-cl.56, TUBB1, TUBB5 |
| Purification: | Immunoaffinity purification |
| Storage: | Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide). |
| Background: | TMP21, a type I transmembrane protein, is a member of the p24 cargo protein family, which is highly enriched in the ER, the Golgi and coat protein (COP) I and II transport vesicles (1,2). TMP21 is involved in protein transport and vesicular targeting. In particular, TMP21 influences APP trafficking by stabilizing nascent APP. The absence of TMP21 leads to enhanced maturation and cell surface accumulation of APP (3). In addition, TMP21 is a non-essential component of the γ-secretase complex with the potential to modulate γ-secretase mediated cleavage and Aβ production without having an effect on ε-secretase activity (4). |
| Caculated MW: | 55 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:200 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information