ARPF003-11 [Polyclonal Antibody]
SNCA/B Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC
Immunogen Range:   A synthetic peptide corresponding to N-terminus of human SNC
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   6620/6622
Swiss Prot:   Q16143/P37840
Synonyms:   MGC110988, NACP, PARK1, PARK4, PD1
Purification:   Immunoaffinity purification
Storage:   Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide).
Background:   Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Caculated MW:   18 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information