ARPF003-11
[Polyclonal Antibody]
SNCA/B Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC |
Immunogen Range: |
A synthetic peptide corresponding to N-terminus of human SNC |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
6620/6622 |
Swiss Prot: |
Q16143/P37840 |
Synonyms: |
MGC110988, NACP, PARK1, PARK4, PD1 |
Purification: |
Immunoaffinity purification |
Storage: |
Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide). |
Background: |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq |
Caculated MW: |
18 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:50
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!