ARPF003-11
[Polyclonal Antibody]
SNCA/B Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC |
| Immunogen Range: |
A synthetic peptide corresponding to N-terminus of human SNC |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
6620/6622 |
| Swiss Prot: |
Q16143/P37840 |
| Synonyms: |
MGC110988, NACP, PARK1, PARK4, PD1 |
| Purification: |
Immunoaffinity purification |
| Storage: |
Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide). |
| Background: |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq |
| Caculated MW: |
18 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:50
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!