ARPF014P-12
[Polyclonal Antibody]
Phospho-PAK1-Thr423/PAK2-Thr402 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
S-ELISA |
| Immunogen Range: |
A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T423 of human PAK1/PAK2/PAK3 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
5058/5062 |
| Swiss Prot: |
Q13153/Q13177 |
| Synonyms: |
MGC130000, MGC130001, PAKalpha |
| Purification: |
Affinity purification |
| Storage: |
Store at 4°C. For long term storage store at -20°C in 100 mM Tris-Cl, 500 mM NaCl, pH 8.0 (0.01% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
| Caculated MW: |
61-74 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!