ARP2736-11 [Polyclonal Antibody]
GLI2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide corresponding to amino acids 46-60 of human GLI2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   2736
Swiss Prot:   P10070
Synonyms:   HPE9, THP1, THP2
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq
Caculated MW:   220 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:500-1:2000
Reacitivity:   Bovine, Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information