ARP8428-11 [Polyclonal Antibody]
STK2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to amino acids 356-375 of human STK24
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   8428
Swiss Prot:   Q9Y6E0
Synonyms:   MST-3, MST3, MST3B, STE20, STK3
Purification:   Affinity purification
Storage:   Store at 4°C on dry atmosphere.After reconstitution with deionized water, store at -20°C or lower.
Background:   The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM
Caculated MW:   50 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information