ARP55851-11
[Polyclonal Antibody]
PSENEN Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide (conjugated to KLH) corresponding to N-terminus 11 amino acids of human PSENEN |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 55851 |
| Swiss Prot: | Q9NZ42 |
| Synonyms: | MDS033, MSTP064, PEN-2, PEN2 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C on dry atmosphere.After reconstitution with sterile water, store at -20°C. |
| Background: | Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq |
| Caculated MW: | 13 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 5-10 ug/mL |
| Reacitivity: | Hamster, Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information