Species: | Mouse |
Applications: | WB IHC ELISA IF |
Immunogen Range: | A synthetic peptide corresponding to C-terminus end of human TUBA1B |
Clonality: | Monoclonal Antibody |
Isotype: | IgG2a |
GENE ID: | 10376 |
Swiss Prot: | P68363 |
Synonyms: | K-ALPHA-1 |
Purification: | Affinity purification |
Storage: | Store at 4°C for short term. For long term storage store at -20°C in 20 mM potassium phosphate buffer, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles. |
Background: | The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins (1). |
Caculated MW: | 52 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:1000 IHC 2.5 ug/mL IF 0.1 ug/mL |
Reacitivity: | Bovine, Chiken, Human, Mouse, Rat |