AMM4744-11 [Monoclonal Antibody]
NEFH Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IF
Immunogen Range:   Native purified bovine NEFH
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   4744
Swiss Prot:   P12036
Synonyms:   NFH
Purification:   Affinity purification
Storage:   Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles.
Background:   Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq
Caculated MW:   180-220 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:5000
IF 1:500
Reacitivity:   Bovine
For research use only. Not intended for diagnostic or therapeutic use!
Additional information