AMM1956-12C
[Monoclonal Antibody]
EGFR Rabbit Monoclonal Antibody (Biotinylated)
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Species: |
Mouse |
Applications: |
IHC |
Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to amino acids 985-996 of human EGFR |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
1956 |
Swiss Prot: |
P00533 |
Synonyms: |
ERBB, ERBB1, HER1, PIG61, mENA |
Purification: |
Affinity purification |
Storage: |
Store at 4°C in 10 mM potassium phosphate buffer, 150 mM NaCl, 2 mM EDTA, pH 7.25 (1% BSA, 0.1% sodium azide). Do not freeze. |
Background: |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq |
Caculated MW: |
175 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:50
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!