AMM23411-11 [Monoclonal Antibody]
SIRT1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to human SIRT1
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   23411
Swiss Prot:   Q96EB6
Synonyms:   SIR2L1
Purification:   Affinity purification
Storage:   Store at -20°C. For long term storage store at -80°C in PBS (0.05% sodium azide, 0.05% proclin 300).Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Caculated MW:   120 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information