AMM8243-11 [Monoclonal Antibody]
SMC1A Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Mouse
Applications:   WB IF
Immunogen Range:   A recombinant protein corresponding to amino acids 402-894 of human SMC1A
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   8243
Swiss Prot:   Q14683
Synonyms:   CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Purification:   Affinity purification
Storage:   Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles.
Background:   Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq
Caculated MW:   145 kDa
Observed MW:   Refer to Figures
Applications:   WB 1-5 ug/mL
IF 5-10 ug/mL
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information