AMM867P-11
[Monoclonal Antibody]
Phospho-CBL-Tyr700 Mouse Monoclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB ELISA |
| Immunogen Range: |
A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y700 of human CBL |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
867 |
| Swiss Prot: |
P22681 |
| Synonyms: |
C-CBL, CBL2, RNF55 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq |
| Caculated MW: |
120 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!