AMM867P-11 [Monoclonal Antibody]
Phospho-CBL-Tyr700 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y700 of human CBL
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   867
Swiss Prot:   P22681
Synonyms:   C-CBL, CBL2, RNF55
Purification:   Affinity purification
Storage:   Store at -20°C in PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide).Avoid freeze/thaw cycles.
Background:   The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Caculated MW:   120 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information