Species: | Mouse |
Applications: | WB IHC IP IF FC |
Immunogen Range: | A recombinant GST fusion protein corresponding to human CDKN1B |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 Kappa |
GENE ID: | 1029 |
Swiss Prot: | P42771 |
Synonyms: | CDKN4, KIP1, MEN1B, MEN4, P27KIP1 |
Purification: | Protein A/G affinity chromatography |
Storage: | Store at 4°C. For long term storage store at -20°C in PBS (0.05% BSA, 0.05% sodium azide). Avoid freeze/thaw cycles. |
Background: | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq |
Caculated MW: | 14 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 0.5-1 ug/mL IHC 0.5-1 ug/mL IF 0.5-1 ug/Ml FC 0.5-1 ug/million cells |
Reacitivity: | Human, Monkey, Mouse, Rat |