AMM1029-12 [Monoclonal Antibody]
CDKN2A Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC IP IF FC
Immunogen Range:   A recombinant GST fusion protein corresponding to human CDKN1B
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   1029
Swiss Prot:   P42771
Synonyms:   CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Purification:   Protein A/G affinity chromatography
Storage:   Store at 4°C. For long term storage store at -20°C in PBS (0.05% BSA, 0.05% sodium azide). Avoid freeze/thaw cycles.
Background:   This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq
Caculated MW:   14 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.5-1 ug/mL
IHC 0.5-1 ug/mL
IF 0.5-1 ug/Ml
FC 0.5-1 ug/million cells
Reacitivity:   Human, Monkey, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information