AMM4072-15 [Monoclonal Antibody]
EPCAM Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   IHC IF ICC
Immunogen Range:   Neuraminidase treated GLS-1 human small cell lung carcinoma line (de Leij L, 1984) The antibody binding epitope has been mapped to the first EGF-like repeat domain (EGF1) amino acids 27-59 of protein (Balzar, 1999; Balzar 2001) This antibody was assigned
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   4072
Swiss Prot:   P16422
Synonyms:   17-1A, 323/A3, CD326, CO-17A, CO17-1A, EGP, EGP-2, EGP34, EGP40, ESA, Ep-CAM, GA733-2, HEA125, KS1/4, KSA, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1, hEGP-2
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in Bioreactor concentrate (0.05% sodium azide). Avoid freeze/thaw cycles.
Background:   This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq
Caculated MW:   40 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:200-1:400
IF 1:10-1:2000
ICC 1:10-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information