Species: | Mouse |
Applications: | IHC IF ICC |
Immunogen Range: | Neuraminidase treated GLS-1 human small cell lung carcinoma line (de Leij L, 1984) The antibody binding epitope has been mapped to the first EGF-like repeat domain (EGF1) amino acids 27-59 of protein (Balzar, 1999; Balzar 2001) This antibody was assigned |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 Kappa |
GENE ID: | 4072 |
Swiss Prot: | P16422 |
Synonyms: | 17-1A, 323/A3, CD326, CO-17A, CO17-1A, EGP, EGP-2, EGP34, EGP40, ESA, Ep-CAM, GA733-2, HEA125, KS1/4, KSA, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1, hEGP-2 |
Purification: | Affinity purification |
Storage: | Store at 4°C. For long term storage store at -20°C in Bioreactor concentrate (0.05% sodium azide). Avoid freeze/thaw cycles. |
Background: | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq |
Caculated MW: | 40 kDa |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:200-1:400 IF 1:10-1:2000 ICC 1:10-1:2000 |
Reacitivity: | Human |