AMM835-11 [Monoclonal Antibody]
CASP2 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   A recombinant protein corresponding to amino acids 32-169 of human CASP2
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   835
Swiss Prot:   P42575
Synonyms:   CASP-2, ICH-1L, ICH-1L/1S, ICH1, NEDD2
Purification:   Affinity purification
Storage:   Store at -20°C in PBS, pH 7.4 (0.1% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq
Caculated MW:   12,14,48 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information