Species: | Mouse |
Applications: | WB IHC ELISA FC |
Immunogen Range: | A recombinant protein corresponding to human NQO1 |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 1728 |
Swiss Prot: | P15559 |
Synonyms: | DHQU, DIA4, DTD, NMOR1, NMORI, QR1 |
Purification: | Affinity purification |
Storage: | Store at 4°C. For long term storage store at -20°C in ascites (0.03% sodium azide). Avoid freeze/thaw cycles. |
Background: | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq |
Caculated MW: | 29 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 FC 1:200-1:400 |
Reacitivity: | Human |