AMM5460-12 [Monoclonal Antibody]
POU5F1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA IF FC
Immunogen Range:   A synthetic peptide corresponding to human POU5F1
Clonality:   Monoclonal Antibody
Isotype:   /
GENE ID:   5460
Swiss Prot:   Q01860
Synonyms:   MGC22487, OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in ascites (0.03% sodium azide). Avoid freeze/thaw cycles.
Background:   This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Caculated MW:   45 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:200-1:1000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information