
| Species: | Mouse |
| Applications: | WB IHC ELISA IF FC |
| Immunogen Range: | A recombinant protein corresponding to human SIRT1 |
| Clonality: | Monoclonal Antibody |
| Isotype: | / |
| GENE ID: | 23411 |
| Swiss Prot: | Q96EB6 |
| Synonyms: | SIR2L1 |
| Purification: | Affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in ascites (0.03% sodium azide). Avoid freeze/thaw cycles. |
| Background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
| Caculated MW: | 120 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 IF 1:200-1:1000 FC 1:200-1:400 |
| Reacitivity: | Human |