Species: | Mouse |
Applications: | WB IHC ELISA IF |
Immunogen Range: | A recombinant protein corresponding to human PRKDC |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 5591 |
Swiss Prot: | P78527 |
Synonyms: | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
Purification: | Affinity purification |
Storage: | Store at 4°C. For long term storage store at -20°C in ascites(0.03% sodium azide). Avoid freeze/thaw cycles. |
Background: | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM |
Caculated MW: | 450 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:200-1:1000 IF 1:200-1:1000 |
Reacitivity: | Human |