AMM5591-17 [Monoclonal Antibody]
PRKDC Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA IF
Immunogen Range:   A recombinant protein corresponding to human PRKDC
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   5591
Swiss Prot:   P78527
Synonyms:   DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in ascites(0.03% sodium azide). Avoid freeze/thaw cycles.
Background:   The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM
Caculated MW:   450 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information