AMM6647-12 [Monoclonal Antibody]
SOD1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   IP
Immunogen Range:   A recombinant protein corresponding to full length human SOD1
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   6647
Swiss Prot:   P00441
Synonyms:   ALS, ALS1, IPOA, SOD, homodimer
Purification:   Affinity purification
Storage:   Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
Caculated MW:   18 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information