ARP9252P-32
[Polyclonal Antibody]
Phospho-RPS6KA5-Thr581 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic phosphopeptide corresponding to residues surrounding Thr581 of human MSK1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
9252 |
Swiss Prot: |
O75582 |
Synonyms: |
MGC1911, MSK1, MSPK1, RLPK |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
MSK1, a mitogen and stress activated protein kinase, is activated by Erk as well as p38 MAPK in response to growth factors and cellular stress, respectively (1). MSK1 resembles RSK because it has two kinase domains connected by a regulatory linker region (2). Phosphorylation of RSK1 at Ser364 and Ser381 is critical for RSK1 activity (3). These sites are analogous to Ser360 and Ser376 of MSK1, which may be important for MSK1 activity as well. |
Caculated MW: |
90 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!