MRP57749-31 [Polyclonal Antibody]
PIWIL1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IP IF
Immunogen Range:   A synthetic peptide corresponding to residues surrounding Asp478 of mouse Miwi
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   57749(Mouse)
Swiss Prot:   Q9JMB7
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The Drosophila piwi gene was identified as being required for the self-renewal of germline stem cells (1). Piwi homologs are well conserved among various species including Arabidopsis, C. elegans, and Homo sapiens (1). Both Miwi and Mili proteins are mouse homologs of Piwi and contain a C-terminal Piwi domain (2). Miwi and Mili bind to Piwi-interacting RNAs (piRNAs) in male germ cells and are essential for spermatogenesis in mice (3-5).
Caculated MW:   90 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information