ARP3837-11 [Polyclonal Antibody]
KPNB1 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Goat
Applications:   WB IHC IF
Immunogen Range:   A synthetic peptide corresponding to human KPNB1
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   3837
Swiss Prot:   Q14974
Synonyms:   MB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
Purification:   Antigen affinity purification
Storage:   Store at -20°C in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq
Caculated MW:   97.2 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.3-1 ug/mL
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information