ARP1741-11
[Polyclonal Antibody]
DLG3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IF |
| Immunogen Range: | A recombinant protein corresponding to SLC12A3 N-terminus (amino acids 74-95) |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 1741 |
| Swiss Prot: | P07858 |
| Synonyms: | FLJ96318, NCCT, TSC |
| Purification: | Affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in PBS, 50% glycerol and 0.09% sodium azide.Avoid freeze/thaw cycles. |
| Background: | This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
| Caculated MW: | 102 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information