ARP23118-13
[Polyclonal Antibody]
MAP3K7IP2 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC ELISA |
| Immunogen Range: |
A synthetic peptide corresponding to 14 amino acids at C-terminus of human MAP3K7IP2 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
23118 |
| Swiss Prot: |
Q9NYJ8 |
| Synonyms: |
FLJ21885, KIAA0733, TAB2 |
| Purification: |
Peptide affinity purification |
| Storage: |
Store at 4°C. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq |
| Caculated MW: |
80 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 5 ug/mL
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!