Species: | Rabbit |
Applications: | WB ELISA ChIP ChIP-seq Dot |
Immunogen Range: | A synthetic peptide (conjugated with KLH) corresponding to Histone H3, acetylated at lysine 27 |
Clonality: | Polyclonal Antibody |
Isotype: | / |
GENE ID: | 8358 |
Swiss Prot: | P68431 |
Synonyms: | H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888 |
Purification: | Affinity purification |
Storage: | Store at -20°C. For long term storage store at -80°C in PBS (0.05% sodium azide, 0.05% Proclin 300).Avoid freeze/thaw cycles. |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq |
Caculated MW: | 17 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:1000 ChIP 1-2 ug Dot 1:25000 |
Reacitivity: | Human |