ARP321-13
[Polyclonal Antibody]
APBA2 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ELISA |
| Immunogen Range: | A synthetic peptide corresponding to 18 amino acids near internal region of human APBA2 |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 321 |
| Swiss Prot: | Q99767 |
| Synonyms: | FLJ25458, FLJ37160, GIDRP86, PSORT |
| Purification: | Affinity purification |
| Storage: | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: | Amyloid β A4 precursor protein-binding family A member 2 (APBA2) is a neuronal adaptor protein that interacts with the amyloid β precursor protein (APP) (1). The amyloid β-protein (Aβ) is the principal component of amyloid plaques, a pathological hallmark of Alzheimer’s disease (2). APBA2 has been shown to stabilize APP metabolism and suppress the secretion of Aβ (3). APBA2 mediates interaction between APP and the neural type I membrane protein Alcadein (Alc) by linking their cytoplasmic domains, thereby forming a tripartite complex of the three proteins in neurons (4). |
| Caculated MW: | 135 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1-2 ug/mL IHC 10 ug/mL |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information