ARP60673-11 [Polyclonal Antibody]
C12orf44 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide corresponding to 16 amino acids near internal region of human C12orf44
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   60673
Swiss Prot:   Q9BSB4
Synonyms:   FLJ11773
Purification:   Affinity purification
Storage:   Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   Atg101 was discovered as a binding protein for Atg13, a component of the ULK1 serine-threonine kinase complex required for autophagy (1-3). Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (4,5). It is generally activated by conditions of nutrient deprivation, but is also associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer (6). The molecular machinery of autophagy was largely discovered in yeast and is directed by a number of autophagy-related (Atg) genes. The ULK1 complex includes both Atg13 and FIP200 and is required for starvation-induced autophagy (7-9). Interaction between Atg101 and Atg13 can be important for the stability and basal phosphorylation of Atg13 and ULK1 (1,2).
Caculated MW:   25 kDa
Observed MW:   Refer to Figures
Applications:   WB 1-2 ug/mL
IHC 5 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information