ARP84433-11
[Polyclonal Antibody]
CARD11 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC IF ICC |
| Immunogen Range: | Amino acids 1-221 human CARMA1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 84433 |
| Swiss Prot: | Q9BXL7 |
| Synonyms: | BIMP3, CARMA1, MGC133069 |
| Purification: | Affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in neat serum.Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq |
| Caculated MW: | 130 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information