AGP7137-11
[Polyclonal Antibody]
TNNI3 Goat Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
ELISA |
Immunogen Range: |
Human TNNI3 |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
7137 |
Swiss Prot: |
P19429 |
Synonyms: |
CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI |
Purification: |
Affinity purification |
Storage: |
Store at 4°C in PBS, pH 7.4 (0.1% sodium azide). |
Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq |
Caculated MW: |
28 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!