ARP54541-11 [Polyclonal Antibody]
DDIT4 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide corresponding to internal region 12 amino acids of human DDIT4
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   54541
Swiss Prot:   Q9NX09
Synonyms:   Dig2, FLJ20500, REDD-1, REDD1, RP11-442H21.1, RTP801
Purification:   Affinity purification
Storage:   Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   REDD1 (REgulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros (1). REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2). Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses (3).
Caculated MW:   28 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.5-1 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information