ARP54541-11
[Polyclonal Antibody]
DDIT4 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A synthetic peptide corresponding to internal region 12 amino acids of human DDIT4 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
54541 |
| Swiss Prot: |
Q9NX09 |
| Synonyms: |
Dig2, FLJ20500, REDD-1, REDD1, RP11-442H21.1, RTP801 |
| Purification: |
Affinity purification |
| Storage: |
Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
REDD1 (REgulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros (1). REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2). Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses (3). |
| Caculated MW: |
28 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 0.5-1 ug/mL
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!