ARP55851-13 [Polyclonal Antibody]
PSENEN Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide corresponding to N-terminus 13 amino acids of human PSENEN
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   55851
Swiss Prot:   Q9NZ42
Synonyms:   MDS033, MSTP064, PEN-2, PEN2
Purification:   Affinity purification
Storage:   Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq
Caculated MW:   13 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.5-1 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information