ARP51651-11 [Polyclonal Antibody]
PTRH2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB ICC
Immunogen Range:   A synthetic peptide corresponding to N-terminus 15 amino acids of human PTRH2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   51651
Swiss Prot:   Q9Y3E5
Synonyms:   BIT1, CGI-147, FLJ32471, PTH2
Purification:   Affinity purification
Storage:   Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   Bit1 is a mitochondrial protein discovered as a regulator of anoikis, a process of apoptosis triggered by the loss of cell adhesion to the extracellular matrix (1,2). Like several other mitochondrial apoptotic regulators (Cytochrome c, Smac, HtrA2, AIF, EndoG), Bit1 is released into the cytoplasm during apoptosis (1,3). Cytoplasmic Bit1 associates with the Groucho family of transcriptional regulator AES (1,4). Interaction between Bit1 and AES promotes apoptosis, and this complex is suppressed by integrin mediated cell attachment.
Caculated MW:   19,21 kDa
Observed MW:   Refer to Figures
Applications:   WB 1-2 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information