AMM1956-11C
[Monoclonal Antibody]
EGFR Rabbit Monoclonal Antibody (Biotinylated)
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DATASHEET
| Species: |
Mouse |
| Applications: |
IHC FC |
| Immunogen Range: |
Native purified EGFR from human epidermoid carcinoma line A431 |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG2b |
| GENE ID: |
1956 |
| Swiss Prot: |
P00533 |
| Synonyms: |
ERBB, ERBB1, HER1, PIG61, mENA |
| Purification: |
Affinity purification |
| Storage: |
Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide). Do not freeze. |
| Background: |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq |
| Caculated MW: |
175 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
FC 1 ug/million cells
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!