AMM5430-11 [Monoclonal Antibody]
POLR2A Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA IF
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding S5 of human POLR2A
Clonality:   Monoclonal Antibody
Isotype:   IgM
GENE ID:   5430
Swiss Prot:   P24928
Synonyms:   MGC75453, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Purification:   Affinity purification
Storage:   Store at 4°C for short term. For long term storage store at -20°C in PBS (0.1% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq
Caculated MW:   250 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human, Yeast
For research use only. Not intended for diagnostic or therapeutic use!
Additional information