AMM5925-14
[Monoclonal Antibody]
RB1 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | IP |
| Immunogen Range: | A recombinant protein corresponding to amino acids 393-572 of human RB1 |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 5925 |
| Swiss Prot: | P06400 |
| Synonyms: | RB, pRb, OSRC, pp110, p105-Rb |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Caculated MW: | 110 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Chiken, Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information