AMMC002-11 [Monoclonal Antibody]
KRT Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC
Immunogen Range:   Native purified from cytoskeleton of human A431 carcinoma cells
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   3851/3852/3853/3854/3856/3858/3860/3875/286887
Swiss Prot:   P05783/P02538/P04259/P13645/P13646/P19013/P13647/P48668/P05787
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles.
Background:   Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).
Caculated MW:   46-58 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information