AMM2099-12
[Monoclonal Antibody]
ESR1 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB IP GSA |
| Immunogen Range: | A recombinant protein corresponding to amino acids 302-595 of human ESR1 |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 2099 |
| Swiss Prot: | P03372 |
| Synonyms: | DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles. |
| Background: | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq |
| Caculated MW: | 66 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1-2 ug/mL |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information