AMM7298-11
[Monoclonal Antibody]
TYMS Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB IHC ELISA IP IF FC |
| Immunogen Range: | A recombinant protein corresponding to human TYMS |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 7298 |
| Swiss Prot: | P04818 |
| Synonyms: | HsT422, MGC88736, TMS, TS, TSase |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles. |
| Background: | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq |
| Caculated MW: | 30 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information