AMM3099-11
[Monoclonal Antibody]
HK2 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Mouse |
Applications: |
WB ELISA |
Immunogen Range: |
A recombinant protein corresponding to full length human HK2 |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 Kappa |
GENE ID: |
3099 |
Swiss Prot: |
P52789 |
Synonyms: |
HK2, DKFZp686M1669, HKII, HXK2 |
Purification: |
Protein G purification |
Storage: |
Store at -20°C in PBS, pH 7.4 (0.1% sodium azide).Avoid freeze/thaw cycles. |
Background: |
Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3). |
Caculated MW: |
102 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000-1:3000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!