AMM4292-11
[Monoclonal Antibody]
MLH1 Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
IHC |
Immunogen Range: |
MLH1 |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG2a |
GENE ID: |
4292 |
Swiss Prot: |
P40692 |
Synonyms: |
COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1 |
Purification: |
Affinity purification |
Storage: |
Store at 4°C in PBS, pH 7.4 (protein base, sodium azide). |
Background: |
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq |
Caculated MW: |
85 kDa |
Observed MW: |
Refer to Figures |
Applications: |
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Reacitivity: |
/ |
For research use only. Not intended for diagnostic or therapeutic use!